| REDUCING NONSELECTIVE PROTEIN ADSORPTION AND CELL ADHESION ON POLYACRYLONITRILE FILMS BY COPOLYMERIZATION OF ACRYLONITRILE WITH α—ALLYL GLUCOSIDE |
| Rui-qiangKou ChaoQu Zhi-kangXu You-yiXu KeYao |
| 关键词：减量法 蛋白质 吸附 聚丙烯腈薄膜 共聚合作用 丙烯腈 α－烯丙基配糖物 |
| 主要内容：In this work,the surface properties of novel sugar-containing polymers,α-allyl glucoside(AG)/acrylonitrile(AN) copolymers,were studied by contact angle,protein adsorption and cell adhesion measurements.It was found that the contact angle of the copolymer films decreased from 68° to 30° with the increase of AG content in the copolymer.The adsorption amount of bovine serum albumin(BSA) and the adhesive macrophage onto the film surface also decreased significantly with increasing α-allyl glucoside content from 0 to 42 wt% in the copolymer.These preliminary results reveal that both the hydrophilicity and the biocompatibility of polyacrylonitrile-based membranes could be improved by copolymerizing acrylonitrile with vinyl carbohydrates. |
| 《高分子科学：英文版》 2003,21(3).-373-376 |
| 全文下载请进入http://hightech.stlib.cn/tpi_1/sysasp/include/index.asp |
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